UNUSUAL PRESENTATION OF MALIGNANT THYMOMA ASSOCIATED NEPHROTIC SYNDROME WITH FOCAL SEGMENTAL GLOMERULOSCLEROSIS: A CASE REPORT

نویسندگان

چکیده

Paraneoplastic syndromes (PS) are the consequences of hormones or immune cross-reactivity produced by a tumor. Nephrotic syndrome (NS) is an extremely rare PS resulting from thymoma. Here, case 55-year-old woman presenting progressive generalized edema and foamy urine reported. The patient’s chest CT scan showed anterior mediastinum with intramural punctate calcification size 8.6x7.0x10.2 cm. was reviewed at multi-dispensary team conference, clinical diagnosis unusual presentation malignant thymoma known as NS. After that, thymectomy kidney biopsy performed. Histopathologic examination Thymoma type B focal segmental glomerulosclerosis, respectively. Therefore, we considered it paraneoplastic nephrotic (PNS), without glucocorticoids, immunosuppressants other drugs to treat thymectomy, her spontaneous resolved first follow-up, proposing causative relationship between two conditions.

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ژورنال

عنوان ژورنال: Journal of Southeast Asian Medical Research

سال: 2023

ISSN: ['2697-5424']

DOI: https://doi.org/10.55374/jseamed.v7.173